General description

Caged Ca²⁺ chelator that undergoes a major and rapid decrease in Ca²⁺-binding affinity upon photolysis. Can be microinjected or permeabilized into cells. May also be useful as a caged Mg²⁺ chelator. K_d (Ca²⁺) = 5 nM; K_d (Mg²⁺) = 2-5 µM.

Caged Ca²⁺ chelator that undergoes a major and rapid decrease in Ca²⁺-binding affinity upon photolysis. Can be microinjected or used with permeabilized cells. May also be useful as caged Mg²⁺ chelator. K_d (Ca²⁺) = 5 nM; K_d (Mg²⁺) = 2-5 µM.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Mulkey, R.M., and Zucker, R.S. 1993. J. Physiol. 462, 243.Zucker, R.S. 1993. Cell Calcium 14, 87.McCray, J.A., et al. 1992. Biochemistry31, 8856.Delaney, K.R., and Zucker, R.S. 1990. J. Physiol.426, 473.Kaplan, J.H., and Ellis-Davies, G.C. 1988. Proc. Natl. Acad. Sci. USA85, 6571.Morad, M., et al. 1988. Science241, 842.

Packaging

5 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)